NAS basically just means “Network Attached Storage” and doesn’t really tell you much about the intended use.
Since your main purpose is to use it as an archive for priceless data, I would lean towards RAIDZ2 or even RAIDZ3, or alternatively a 2-way or 3-way mirror. Personally, I prefer the RAID-Z configurations because they usually offer more usable capacity, and I/O performance is secondary for this kind of use.
I’m in a very similar scenario: I want to store important and irreplaceable data as safely as possible. I do this with TrueNAS Core, using a 6-wide RAIDZ2. The drives are used Enterprise HDDs (HGST 6TB SAS),connected via an HBA in IT mode. For my purposes, these drives should still have plenty of life left, and I bought them about two years ago for roughly €45 each (~€7/TB at the time, which I thought was pretty reasonable).
ECC RAM is a real point of debate in the community, but I personally didn’t want to risk a few euros’ worth, so I went with a Xeon CPU and ECC RAM. This should give me some protection against bit flips, bit rot, and issues during scrubs.
Looking forward, I also need to think about other risks:
my own mistakes (accidentally destroying a pool, deleting data)
and other disasters like fire, lightning, water damage, or theft.
No amount of RAID-Z3 will protect you against thoss (remember:“RAID is not a backup”).
So I’ll need a practical off-site backup strategy as well.
24/7/365…this is also one of those topics where opinions differ… For me, I only fire up the NAS when I actually need it—running it 24/7 would be overkill.
If, in your scenario, you actually use the NAS several times a day, then keeping it running continuously would be worth considering.
If you end up running it continuously, you might also want to consider a UPS, since a sudden power outage can cause serious problems.
But let’s be honest… all in all, the term “power-efficient” slowly starts to take on a different meaning …
(Although it’s still definitely better compared to a large enterprise server that consumes 1000 watts or more.)