Reviving this thread to (1) re-focus the original question, and (2) share some data that may be interesting.
The question I really meant to ask from the start is: is a C3758-based TrueNAS Scale system, with SSDs and 10Gbe network, likely to be bottlenecked by the CPU, when used exclusively for storage?
In my case, the TrueNAS server is used strictly for storage, the only service I have running on it is Nextcloud. Consider this hypothetical: all at once, someone is syncing 100s of GB of photos on their phone via Nextcloud, while another person is doing video editing (their working directory is hosted on the TrueNAS system), while two others are independently streaming two different 4k Bluray rips (no transcoding). While this scenario is almost entirely I/O bound, the CPU will be active - but will it be a bottleneck?
That question isn’t directly answered, but this ServeTheHome review seems to suggest the C3758 is more than capable: iXsystems TrueNAS Mini X+ ZFS NAS Review.
One of the things mentioned above was the worry that Xeon D-1541 has higher power consumption than C3758. Of course the power draw ceiling (i.e. TDP) is higher, but I expected idle draw to be similar - but I was wrong! I put a Kill-a-Watt meter on my A2SDi-8C-HLN4F (C3758) TrueNAS system in-situ for a couple days to get the average power draw: about 52 Watts.
Then I replaced the main board with the X10SDV-TLN4F (D-1541) - I also increased the memory from 2x8GB UDIMM to 2x16GB UDIMM. The rest of the system was unchanged. Average power draw over 24 hours went up to about 67 Watts.
That was surprising. Then I thought some of that extra draw might be due to the on-board NICs which I’m not actually using (opting for the Solarflare PCIe NIC). I disabled those last night. (And for anyone who stumbles on this thread and wants to do the same: you can’t disable the Ethernet controllers in the BIOS, you have to do it via physical jumpers on the board itself.) I did this last night, so only about 12 hours on the Kill-a-Watt so far, but it’s down to about 60 Watts.
So it indeed looks like the A2SDi-8C-HLN4F has a lower power draw than the X10SDV-TLN4F, though the doubled RAM likely accounts for some of the added draw. Now I’m running some power consumption tests on the A2SDi-8C-HLN4F alone - stock TrueNAS install, only a single SATA SSD for OS. I’ll disable the 4x on-board i350 NICs and also try different amounts of memory, including UDIMM vs RDIMM.
Ultimately, it’s looking like I’ll move back to the A2SDi-8C-HLN4F, as long as I’m confident the CPU itself is unlikely to be a bottleneck.