Top right hand corner there is a Clipboard Icon that is called “Jobs”
If nothing is listed here as an active task then it means no replication jobs or other long running tasks are currently going on. You should be safe to shut down or restart. Of course this doesn’t track client activity, such as sharing being used, or Apps doing work. You can check Sharing → SMB/NFS and look at client sessions to see if anybody is actively using the shares. Apps you will have to refer to those software’s docs to check activity
That said, drives tend to always be active, there are lots of system / SMART / ZFS things always going on behind the scenes. You should be able to shutdown safely while that is happening though.
SMR, Shingled Magnetic Recording. It is a way to put more data on a drive, however it requires a heavy amount of re-writing data. This kind of drive is not suitable for ZFS file system.
Here is a link for HGST/Seagate SMR drives. See where you drive falls, hopefully in the CMR category. If it’s SMR, It may be doing something, reorganizing the data. You can shut it down properly if desired.