Have Truenass scale General Guide for settings on all Flash Storages?

Have Truenass scale General Guide for settings on all Flash Storages?
For me is important what should be considered in this build for General setting of the VDEV, Storage option (Like Trim enabled) and additionally configuration to avoid overhead. Is necessary sutra off some standart/ default configuration or move only metadata in Memory considering speed of NVME SSD? What shod be done for optimization of the workload if you use different protocols and in relation of the workload?

This greatly depends on your use case. It is not a One Size Fits All.

That I know, but there is nothing what shoud bee looking for if you stat build and General information. I go thru Trena’s documentation but more were learn for Youtube videos as from the official pages for here on forums.
I think it shod be specified paths, what shod be done for if you use spinning rust, or mixed mode or all Ssd and also other based on the workload what you run.

I will provide a link, if you have not read it, you need to as it will help you with part of your answer. You need to understand this stuff. Youtube videos are typically outdated so use at your own peril.

There is actually quite a bit of information in the Resources section of these forums.

As for general guidelines for SSD/NVMe, you asked a lot of questions like TRIM, Workload Optimizations, Protocols. The information is here but not necessarily consolidated. Feel free to consolidate it into a nice user friendly user guide and a lot of people will appreciate the effort you put into it. But I think to create a document like this, it will need to take into consideration all sort of variables such as Use Case, System Speed, RAM Amount, Storage Capacity, Block Storage, various Protocols for various Operating Systems (like MacOS or Windows or Linux). Network speed and connectivity, CPU and RAM Speed. So many factors.

There will not be a single answer to fit all scenarios and I feel you are asking for that.

I’m certain you will take a look at the resources and find the answers you want, and use the new TrueNAS AI or Google searching works very well also.

As for if you should use TRIM, that depends on your Use Case. For a home system I would not enable TRIM, however you could test your system with TRIM off and then with TRIM on. Does it make a difference for you?

I hope some of this helps you find the answers you desire.

Good Luck.