Until you have the backup config, and in any case the same version of the actual os ( CORE 12.0-U8.1), is possible fresh-reinstall n times without losing anything 
The only thing… i dont know if upload the CORE 12.0-U8.1 config into the last version can work properly. Never tried (only from minor release to other, without problem).
Only in my personal opinion: given that with the configuration backup and an ISO it is possible to quickly restore the system, that i don’t have “location” problem to physically change disk, and that in case of some hour of “down” the world dosnt end 
… i opted for a simple stripe boot pool. I keep a second SSD drive (at least always have an usb stick) ready for fast install, in case something bad happen, but not more. Also, look at this if you dont know, really usefull!!!
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