NVIDIA GPUs not working and nvidia-smi fails to communicate with NVIDIA drivers

As I’ve worked my way through this thread (thank you to all who have contributed!) I finally got to the point where my 1080 was recognized:

and the GPU appeared as a viable contender in the PleX App settings:

However, when I hit “Update” I was greeted with:

More info:

Version info for PleX:
App: v1.42.1.10060-4e8b05daf
Version: v1.2.10

TrueNAS Scale: Version: 25.04.2.1

Where next?

Thanks for any info
Kuyper